London Irish have slipped to five straight Aviva Premiership Rugby defeats since beating Harlequins 18-13 at Madejski Stadium in round 5, the Exiles have not been victorious at Reading in the Premiership since that encounter.
Gloucester Rugby ended a five game losing run in the Premiership with their 12-6 win over Worcester at Kingsholm on Sunday. Gloucester’s solo away victory in the tournament since early February was 22-16 at Newcastle on 29th September.
Both Premiership fixtures between the clubs last season were won by the away side on the day, whilst Gloucester have won on their last two visits to Madejski Stadium in all competitions.
Referee: Andrew Small (95th Premiership game).
Assistant Referees: Nigel Carrick & Paul Burton. TMO: Graham Hughes.